DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20200011

Analysis of risk factors behind keloid

Anbumalar Manoharan, Sowmya Manasa Rao

Abstract


Background: Keloids are firm, thickened, bosselated tumors with fibrous tissue which expands beyond the original injury with common sites being presternum, shoulder, ear lobes. They are more common in Blacks and Hispanics than Caucasians. As there is paucity of studies from South India, this study is done to identify the epidemiological features and analyse the risk factors involved in keloid formation and compare it with previous studies.

Methods: 60 subjects were included in the study. Keloid was diagnosed clinically and factors such as the age at presentation, gender, site, size, duration, number and predisposing factors to keloid formation were assessed among them for a period of 18 months.

Results: Most of the patients were in the age group of 20-40 years and maximum were females. Majority of patients around 51.67% were affected in chest followed by shoulder (20%). In our study 61.67% patients had keloids of size ≤5 cm and 23 (38.33%) patients had size >5 cm. Most of the patients (41.67%) had keloids of <2 years duration. Maximum number of the patients (68%) had single keloid. 50% of the patients had keloids which occurred after trauma followed by acne (15%), surgery (10%) and herpes zoster (10%), burns (5%). 10% of the patients had spontaneous onset of keloids.

Conclusions: The epidemiological features found in this study were similar to the studies conducted in the different parts of the world. Elimination of exacerbating factors will prevent further keloid formation thereby playing a crucial role in the management.

 


Keywords


Keloid, Trauma, Acne, Surgery

Full Text:

PDF

References


Al-Attar A, Mess S, Thomassen JM, Kauffman CL, Davison SP. Keloid pathogenesis and treatment. Plast Reconstr Surg. 2006;117:286–300.

Wheeland RG. Keloids and hypertrphic scars. In: Arndt KA, Robinson JK, Leboit PE, Wintroub BU (eds). Cutaneous Medicine and Surgery. Philadelphia: Saunders Elsevier; 1996: 900–905.

Hawkins HK. Pathophysiology of the burn scar. In: Herndon DN (ed). Total Burn Care. Philadelphia; Saunders Elsevier; 2007: 608–619.

Murray JC. Keloids and hypertrophic scars. Clin. Dermatol. 1994;12:27–37.

Niessen FB, Spauwen PH, Schalkwijk J, Kon M. On the nature of hypertrophic scars and keloids: a review. Plast Reconstr Surg. 1999;104:1435–58.

Brissett AE, Sherris DA. Scar contractures, hypertrophic scars, and keloids. Facial Plast Surg. 2001;17:263-72.

Akoz T, Gideroglu K, Akan M. Combination of different techniques for the treatment of earlobe keloids. Aesthetic Plast Surg. 2002;26:184-8.

Ketchum LD, Cohen IK, Masters FW. Hypertrophic scars and keloids. Plast Reconstr Surg. 1974;53:140-53.

Darzi MA, Chowdri NA, Kaul SK, Khan M. Evaluation of various methods of treating keloids and hypertrophic scars: A 10 year follow up study. Br J Plast Surg. 1992;45:374-9.

Berman B, Harlan BC. Keloids. J Am Acad Dermatol. 1995;33:117-23.

Cosman B, Crickelair GF, Ju DMC, Gaulin JC. The surgical treatment of keloids. Plast Reconstr Surg. 1961;27(4):335-58.

Murray JC. Keloids and hypertrophic scars. Dermatol Clin. 1993;11:697–707.

Kelly AP. Keloids. Dermatol Clin. 1988;6:413-24.