A study of clinico pathological spectral correlation in multibacillary leprosy

Authors

  • Anita Sanker Department of Dermatology and Venereology, Government Medical college Manjeri, Malappuram, Kerala, India
  • P. S. Mathew Department of Dermatology and Venereology, Century hospital, Mulakkuzha, Alappuzha, Kerala, India
  • G. Nandakumar Department of Pathology, Government Medical college, Thiruvananthapuram Kerala, India
  • Sandhya George Department of Dermatology and Venereology, Government Medical college Manjeri, Malappuram, Kerala, India
  • V. G. Binesh Department of Dermatology and Venereology, Government Medical college, Thrissur, Kerala, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20200600

Keywords:

Borderline, Histopathological correlation, Lepromatous, Multibacillary leprosy, Tuberculoid

Abstract

Background: Leprosy expresses itself in different clinico-pathological forms, depending on the immune status of the host.The diagnosis and classification of leprosy have traditionally been based on the clinical examination with additional information from skin smears and histopathological examination. Very often, disparities between clinical and histopathological findings are observed. This study was aimed to correlate between clinical and histopathological spectral correlation of newly diagnosed multibacillary leprosy cases for a period of 1 year.

Methods: The study was conducted in the Department of Dermatology and Venereology, Government Medical College, Thiruvananthapuram, for a period of 1 year. All newly diagnosed multibacillary leprosy cases were included.

Results: A total of 40 patients with clinically diagnosed multi bacillary leprosy were studied. Maximum numbers of leprosy patients studied were in the age group of 40-49 years. Maximum clinical and histopathological correlation was found in 75% (9/12) in lepromatous leprosy and least correlation of 44.44% was noted in borderline lepromatous (4/9).

Conclusions: In this study maximal clinico-histopathological spectral correlation was found in lepromatous  spectrum. The percentage of correlation was considerably less in all the other groups.

Author Biography

Anita Sanker, Department of Dermatology and Venereology, Government Medical college Manjeri, Malappuram, Kerala, India

Assistant Professor,Department of D&V Govt. Medical college Manjeri, Malappuram Dist. Kerala state.

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Published

2020-02-24

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Original Research Articles