Clinical profile of 50 premenopausal women with hirsutism

Authors

  • Sonal Panjwani Department of Dermatology, Venereology and Leprosy, N.S.C.B. Subharti Medical College and Associated, Chhatrapati Shivaji Subharti Hospital, Meerut, Uttar Pradesh
  • Arvind Krishna Department of Dermatology, Venereology and Leprosy, N.S.C.B. Subharti Medical College and Associated, Chhatrapati Shivaji Subharti Hospital, Meerut, Uttar Pradesh
  • Garima Singh Department of Dermatology, Venereology and Leprosy, N.S.C.B. Subharti Medical College and Associated, Chhatrapati Shivaji Subharti Hospital, Meerut, Uttar Pradesh
  • Divya Arora Department of Dermatology, Venereology and Leprosy, N.S.C.B. Subharti Medical College and Associated, Chhatrapati Shivaji Subharti Hospital, Meerut, Uttar Pradesh

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20191767

Keywords:

Hirsutism, Acne, Severity, Menstrual irregularities

Abstract

Background: Hirsutism is a common condition, affecting up to 10% of women and may be associated with signs and symptoms of hyperandrogenism. The aim of this study was to study the clinical characteristics of patients presenting with hirsutism and to correlate the severity of hirsutism with the presence of these features.

Methods: A hospital based, cross sectional prospective study was conducted on 50 patients with clinically diagnosed hirsutism. Scoring of hirsutism was done using modified Ferriman –Gallwey scoring system following which a complete history was taken and thorough examination of all patients in the study group was carried out for features associated with hirsutism.

Results: Maximum (60%) patients had mild hirsutism, 30% had moderate hirsutism and 10% patients had severe hirsutism. Acne was the most commonly occurring clinical feature, occurring in 50% of the patients followed by menstrual irregularities in 46%, striae and obesity in 42% and acanthosis nigricans in 40% of the patients. Other features seen were androgenic alopecia in 26%, infertility in 16.67% and deepening of voice in 4% of participants.

Conclusions: Hirsutism is a multifaceted condition and this study highlights the need for a thorough clinical examination in order to identify possible associated conditions which may provide significant clues for the underlying cause of hirsutism.

References

Rosenfield RL. Clinical practice. Hirsutism. N Engl J Med. 2005;353(24):2578-88.

Wendelin, DS, Pope DN, Mallory SB. Hypertrichosis. J Am Acad Dermatol. 2003;48(2):161–79.

Ferriman D, Gallwey JD. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab. 1961;21:1440-7.

Sharma D, Shanker V, Tegta G, Gupta M, Verma GK. Clinico- investigative Profile of Patients of Hirsutism in a Tertiary Level Institution. Int J Trichol. 2012;4(2):69-74.

de Berker DAR, Messenger AG, Sinclair RD. Disorders of hair. In: Burns T, Breathnach S, Cox N, Griffiths C, eds. Rook’s Textbook of Dermatology. 7th ed. Oxford: Blackwell Science; 2004.

Hunter MH, Carek PJ. Evaluation and treatment of women with hirsutism. Am Fam Physician. 2003;67:2565–72.

Sharma NL, Mahajan VK, Jindal R, Gupta M, Lath A. Hirsutism: Clinico-investigative profile of 50 Indian patients. Indian J Dermatol. 2008;53:111-4.

Al-Khawajah MM, Fouda Neel MA. Women with clinically significant hirsutism always have detectable endocrinological abnormalities. J Eur Acad Dermatol Venereol. 1997;9(3):226–31.

Chhabra S, Gautam R, Kulshreshtha B, Prasad A, Sharma N. Hirsutism: A Clinico-investigative Study. Int J Trichol. 2012;4(4):246.

Malik, LM, Khursheed K, Haroon TS, Malik MA. An aetiological study of moderate to severe hirsutism. Pak J Med Sci. 2007;23(2):167-71.

Sharma D, Shanker V, Tegta G, Gupta M, Verma GK. Clinico- investigative Profile of Patients of Hirsutism in a Tertiary Level Institution. Int J Trichol. 2012;4(2):69-74.

Ansarin H, Aziz-Jalali M-H, Rasi A, Soltani-Arabshahi R. Clinical presentation and etiologic factors of hirsutism in premenopausal Iranian women. Arch Iran Med. 2007;10(1):7–13.

Jahanfar S, Eden JA. Idiopathic Hirsutism or Polycystic Ovary Syndrome? Aust N Z J Obstet Gynaecol. 1993;33(4):414–6.

Lakhani SJ, Lakhani O, Raval RC. A study of endocrine profile in premenopausal women with hirsutism. J Intgr Health Sci. 2014;2(2):17-22

Puri N. A study on the clinical and hormonal profile of patients with hirsutism. Dermatol Online J. 2012;3(2):88–91.

Zargar AH, Wani AI, Masoodi SR, Laway BA, Bashir MI, Salahuddin M. Epidemiologic and Etiologic Aspects of Hirsutism in Kashmiri Women in the Indian Subcontinent. Fertil Steril. 2002;77(4):674–78.

Sonino N, Fava GA, Mani E, Belluardo P, Boscaro M. Quality of life of hirsute women. Postgrad Med J. 1993;69(809):186–9.

Paulson JD, Haarmann BS, Salerno RL, Asmar P. An investigation of the relationship between emotional maladjustment and infertility. Fertil Steril. 1988;49(2):258–62.

Downey J, Yingling S, McKinney M, Husami N, Jewelewicz R, Maidman J. Mood disorders, psychiatric symptoms, and distress in women presenting for infertility evaluation. Fertil Steril. 1989;52(3):425–32.

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Published

2019-04-26

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Original Research Articles