DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20185508

A study of topical steroid induced facial dermatosis in Andaman and Nicobar Islands and to analyse the role of Demodex mite in its pathogenicity

Mansi Srivastava, Pradeep Balasubramanian, Anjali J. Anil

Abstract


Background: Topical corticosteroids (TCs) are widely abused all over our country due to its short term benefits and effortless over the counter availability. The rate of its abuse is more so in Andaman & Nicobar Islands (A&N). Henceforth we conducted a study to evaluate the topical steroid induced facial dermatosis (TSFD) in A&N and to analyse the role of demodex mite in its pathogenicity.

Methods: 58 patients with TSFD participated in this study. Details such as demography of patient, topical steroid used, duration of usage, reason behind its usage and facial dermatosis of the TSDF developed were collected. Following this, standardized surface skin biopsy (SSSB) was performed to assess the density of demodex mite. The details were statistically analysed.

Results: TSFD were predominantly seen in female of age group between 20 and 30 years. It was commonly misused to get rid of acne, pigmentation, tinea faciei and as a fairness cream. The commonly misused TCs were betamethasone cream followed by mometasone. It was commonly advised by pharmacists, friends, relatives, beauticians and GPs. Papules, pustules, photosensitivity and erythema were the commonly encountered adverse events. Microscopic examination of SSSB was negative in all the patients.

Conclusions: The study depicts rampant and irrational use of TCs in our population. Though the demodex mites were absent in the patients studied, further studies with larger sample size and in different ethnicity needs to be done to affirm its role in the pathogenicity of TSFD.


Keywords


Topical steroid facial dermatosis, Demodex mites

Full Text:

PDF

References


Shih YL, Huang YH, Ho HC, Yang CH. Topical Steroid Induce Demodicidosis as a presentation of Hemifacial Rosacea-Like Lesion. Dermatol Sinica. 2009;27(2):111-6.

Lunder T. Density of Demodex folliculorum in perioral dermatitis. Acta Derm Venereol. 2005;85:211-5.

Zhao YE, Peng Y, Wang XL, Wu LP, Wang M, Yan HL, Xiao SX. Facial dermatosis associated with Demodex: a case-control study. Journal of Zhejiang University SCIENCE B. 2011;12(12):1008-15.

Mahar S, Mahajan K, Agarwal S, Kar HK, Bhattacharya SK. Topical corticosteroid misuse: the scenario in patients attending a tertiary care hospital in New Delhi. Journal of clinical and diagnostic research: JCDR. 2016;10(12):16.

Nagesh TS, Akhilesh A. Topical steroid awareness and abuse: a prospective study among dermatology outpatients. Indian J Dermatol. 2016;61(6):618.

Sinha A, Kar S, Yadav N, Madke B. Prevalence of topical steroid misuse among rural masses. Indian journal of dermatology. 2016;61(1):119.

Forton F, Seys B. Density of Demodex folliculorum in rosacea: a case‐control study using standardized skin‐surface biopsy. Br J Dermatol. 1993;128(6):650-9.

Kaur T, Jindal N, Bansal R, Mahajan B. Facial demodicidosis: A diagnostic challenge. Indian J Dermatol. 2012;57(1):72.

The Drugs and Cosmetics Rules, 1945. Ministry of Health and Family Welfare, Government of India.]. Available at http://www.cdsco.nic.in/writereaddata/ 2016Drugs%20and%20Cosmetics%20Act%201940%20&%20Rules%201945.pdf. Accessed on 15 December 2018.

What Over-the-Counter Treatments Are There For Atopic Dermatitis? Available at https://atopic dermatitis.net/medications-over-the-counter/. Accessed on 15 December 2018.