Cutaneous sarcoidosis: a marker of underlying systemic disease

Authors

  • L. Satyanka Department of DVL, Maharajah Institute of Medical Sciences, Nellimarla, Vizianagram, Andhra Pradesh, India
  • K. V. T. Gopal Department of DVL, Maharajah Institute of Medical Sciences, Nellimarla, Vizianagram, Andhra Pradesh, India
  • P. V. Krishnam Raju Department of DVL, Maharajah Institute of Medical Sciences, Nellimarla, Vizianagram, Andhra Pradesh, India
  • B. Rekha Rani Department of DVL, Maharajah Institute of Medical Sciences, Nellimarla, Vizianagram, Andhra Pradesh, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20222733

Keywords:

Plaque sarcoidosis, Lung fibrosis, Mortimer’s malady

Abstract

Sarcoidosis/Mortimer’s malady is a multisystem disease defined by presence of epithelioid cell granulomas without caseation in various organs.It involves mainly the lungs, eyes, skin, lymph node etc. We reported a 40 year old female who presented with multiple plaques over different regions of the body with past history of ulcerated lesion of scalp which healed with cicatricial alopecia. On thorough evaluation she was found to have involvement of multiple internal organs. Based on the clinical features and histopathological findings, a diagnosis of cutaneous sarcoidosis (plaque type) was made. Patient treated with systemic and topical corticosteroids resulting in marked improvement in her skin lesions were seen and pulmonary complaints also resolved.

Author Biographies

L. Satyanka, Department of DVL, Maharajah Institute of Medical Sciences, Nellimarla, Vizianagram, Andhra Pradesh, India

Department of Dermatology Venerology and Leprology,

final year post graduate  

K. V. T. Gopal, Department of DVL, Maharajah Institute of Medical Sciences, Nellimarla, Vizianagram, Andhra Pradesh, India

Department of Dermatology Venerology and Leprology,

professor and HOD

P. V. Krishnam Raju, Department of DVL, Maharajah Institute of Medical Sciences, Nellimarla, Vizianagram, Andhra Pradesh, India

Department of Dermatology Venerology and Leprology,

professor and HOD

B. Rekha Rani, Department of DVL, Maharajah Institute of Medical Sciences, Nellimarla, Vizianagram, Andhra Pradesh, India

Department of Dermatology Venerology and Leprology,

professor

References

Sacchidanand S, Oberai C, Inamadar AC. IADVL Textbook of Dermatology. 4th ed. India: Bhalani Publishing House; 2015.

Griffiths CEM, Barker J, Bleiker TO, Chalmers R, Creamer D. Rook's Textbook of Dermatology. 9th ed. Manchester, UK: Wiley; 2016.

Samtsov AV. Cutaneous sarcoidosis. Int J Dermatol. 1992;31(6):385-91.

Moschella SL, Crepley TG. Diseases of the mononuclear phagocytic system. In: Fletcher J, eds. Moschella and Hurley Dermatology. 3rd ed. Philadelphia: Saunders; 1992: 1064-1075.

Katta R. Cutaneous sarcoidosis: a dermatologic masquerader. Am Fam Physician. 2002;65(8):1581-4.

Mañá J, Marcoval J, Graells J, Salazar A, Peyrí J, Pujol R. Cutaneous involvement in sarcoidosis. Relationship to systemic disease. Arch Dermatol. 1997;133(7):882-8.

Mohanty R, Singh SN, Bhattamishra AB. Cutaneous sarcoidosis without systemic manifestations. Indian J Dermatol. 2009;54:80-2.

Lever WF, Schamberg-Lever G. Histopathology of the skin. 7th ed. Philadelphia: Lippincott; 1990: 252-256.

Lynch JP, Kazerooni EA, Gay SE. Pulmonary sarcoidosis. Clin Chest Med. 1997;18(4):755-85.

Gautam M, Patil S, Munde P. Skin as a marker of internal disease: a case of sarcoidosis. Indian J Dermatol. 2011;56(4):439-41.

Reddy RR, Shashi KBM, Harish MR. Cutaneous sarcoidosis - a great masquerader: a report of three interesting cases. Indian J Dermatol. 2011;56(5):568-72.

Talwar D, Talwar D, Iyer H. Pulmonary Sarcoidosis. Indian J Rheumatol. 2021;16:47-57.

Dammacco R, Biswas J, Kivelä TT, Zito FA, Leone P, Mavilio A, et al. Ocular sarcoidosis: clinical experience and recent pathogenetic and therapeutic advancements. Int Ophthalmol. 2020;40(12):3453-67.

Elavarasi A, Jain N, Rajeshwari M. Sarcoidosis: A rare cause of thyroiditis. Lung India. 2021;38(5):494-6.

Jadotte YT, Hay RA, Salphale A, Mocellin S, Kumar S, Niazi A, et al. Interventions for cutaneous sarcoidosis. Milken Institute. 2018.

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Published

2022-10-27