An unusual presentation of Gomm-Button disease: a diagnostic enigma

Nagapadma Lakamsani, Sridevi K., Ramamurthy D. V. S. B., Senthil Kumar A. L., Akshay Jain Salecha


Gomm-Button disease (Sweet syndrome) typically presents with abrupt onset of tender skin lesions accompanied by fever and neutrophilia. Histopathology shows the presence of dense neutrophilic infiltrates, oedema without vasculitis. One of the criteria for diagnosis of sweets syndrome is the absence of vasculitis. However, recent reports suggest that vasculitis should not exclude the diagnosis. We present a case of Sweet syndrome with an atypical clinical and histopathological presentation.



Sweet syndrome, Tender subcutaneous and erythematous plaques, Neutrophilic infiltrate in the upper dermis, Leukocytoclastic vasculitis

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