The association of acne vulgaris with smoking in men: a hospital based study

Authors

  • Abhineetha Hosthota Department of Dermatology, The Oxford Medical College Hospital And Research Centre, Bangalore, Karnatak, India
  • Swapna Bondade Department of Psychiatry, The Oxford Medical College Hospital And Research Centre, Bangalore, Karnatak, India
  • Renu K Department of Dermatology, The Oxford Medical College Hospital And Research Centre, Bangalore, Karnatak, India
  • Swati Braroo Department of Psychiatry, The Oxford Medical College Hospital And Research Centre, Bangalore, Karnatak, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20171468

Keywords:

Smoking, Acne vulgaris, Nicotine, Male

Abstract

Background: Acne is a multifactorial dermatosis which occurs often during early adulthood with different grades of severity. The factors contributing to the formation of acne include genes, hormones, iatrogenic, psychological, and environmental and occupation. Our article presents the findings on a possible impact of smoking on acne.

Methods:  This study was conducted to evaluate smoking habits in 126 male acne patients in the age group of 15-45 years. Equal number of age and gender matched healthy controls were taken after consent. These subjects were administered a semi structured proforma to collect socio demographic details. Acne was graded taking into account the predominant lesions and smokers were administered Fagerstrom Test for Nicotine Dependence.

Results: Among the total subjects, 28.57% of cases and 15.87% of controls were smokers. In acne patients the number of cigarettes smoked was more as compared to controls. There was positive correlation between the number of cigarettes and the grading of the acne(r=0.4515). The risk of acne was 2.12 times more in smokers than in non-smokers.

Conclusions: Various studies have reported that smoking may play a role in pathogenesis of acne. Compelling evidence shows that higher nicotine dependence will exacerbate acne. So the association between the two cannot be excluded. The effect of smoking on the course of acne is still inexplicit.

 

Author Biographies

Swapna Bondade, Department of Psychiatry, The Oxford Medical College Hospital And Research Centre, Bangalore, Karnatak, India

Associate Professor

Department of Psychiatry

Renu K, Department of Dermatology, The Oxford Medical College Hospital And Research Centre, Bangalore, Karnatak, India

Senior resident

Department of Dermatology

 

Swati Braroo, Department of Psychiatry, The Oxford Medical College Hospital And Research Centre, Bangalore, Karnatak, India

Senior Resident

Department of Psychiatry

References

Klaz I, Kochba I, Shohat T, Zarka S, Brenner S. Severe acne vulgaris and tobacco smoking in young men. J Invest Dermatol. 2006;126(8):1749-52.

Cunliffe WJ, Simpson NB: Disorders of the sebaceous glands. In: Rook/Wilkinson/Ebling textbook of dermatology Edited by: Champion RH, Burton JL, Burns DA, Breathnach SM. Oxford: Blackwell Science; 1998: 1951-2.

Just-Sarobe M. Smoking and the skin. Actas Dermosifiliogr. 2008;99:173-84.

Durai PC, Nair DG. Acne vulgaris and quality of life among young adults in South India. Indian J Dermatol. 2015;60:33-40.

Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO. The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire. British Journal of Addiction. 1991;86(9):1119-27.

Duquia RP, de Almeida HL Jr, Breunig JA, Souzat PR, Göellner CD. Most common patterns of acne in male adolescents: a population-based study. Int J Dermatol. 2013;52(5):550-3.

Schäfer T, Nienhaus A, Vieluf D, Berger J, Ring J. Epidemiology of acne in the general population: the risk of smoking. Br J Dermatol. 2001;145(1):100-4.

C Aguirre. Understanding Male Skin - The International Dermal Institute. Available at www.dermalinstitute.com/us/library/73_article_Understanding_Male_Skin.html Accessed on 20th May 2016.

Cibula D, Hill M, Vohradnikova O, Kuzel D, Fanta M, Zivny J. The role of androgens in determining acne severity in adult women. Br J Dermatol. 2000;143(2):399-4.

Seirafi H, Farnaghi F, Vasheghani-Farahani A, Alirezaie NS, Esfahanian F, Firooz A, et al. Assessment of androgens in women with adult-onset acne. Int J Dermatol. 2007;46(11):1188-91.

Thomsen SF, Sorensen LT. Smoking and skin disease. Skin Therapy Lett. 2010;15:4-7.

Freiman A, Bird G, Metelitsa AI, Barankin B, Lauzon GJ. Cutaneous effects of smoking. J Cutan Med Surg. 2004;8(6):415-23.

Sela BA. Dermatological manifestations of smoking. Harefuah. 2002;141(8):736-40.

Model D. Smoker's face: an underrated clinical sign? Br Med J. 1985;291:1760-2.

Sullivan TP, Elgart GW, Kirsner RS. Pemphigus and smoking. Int J Dermatol. 2002;41:525-31.

Motley RJ, RhodesJ, Ford GA, Wilkinson SP, Chesner IM, Asquith P, Et al. Time relationships between cessation of smoking and onset of ulcerative colitis. Digestion. 1987;37:125-7.

Axell T, Henricsson V. Association between recurrent aphthous ulcers and tobacco habits. Scand J Dent Res. 1985;93:239-42.

Wolf R, Orion E, Matz H, Maitra S, Rowland-Payne C. Smoking can be good for you. J Cosmet Dermat. 2004;3:107–11.

Theilig C, Bernd A, Ramirez-Bosca A, Görmar FF, Bereiter-Hahn J, Keller-Stanislawski B, et al. Reactions of human keratinocytes in vitro after application of nicotine. Skin Pharmacol. 1994;7(6):307-15.

Pelle E, Miranda EP, Fthenakis C, Mammone T, Marenus K, Maes D. Cigarette smoke-induced lipid peroxidation in human skin and its inhibition by topically applied antioxidants. Skin Pharmacol Appl Skin Physiol. 2002;15:63–8.

Capitanio B, Sinagra JL, Ottaviani M, Bordignon V, Amantea A, Picardo M. Acne and smoking . Dermatoendocrinol. 2009;1:129–35.

Handelman GJ, Packer L, Cross CE. Destruction of tocopherols, carotenoids and retinol in human plasma by cigarette smoke. Am J Clin Nutr. 1996;63(4):559–65.

Monfrecola G, Riccio G, Savarese C, Posteraro G, Procaccini EM. The acute effect of smoking on cutaneous microcirculation blood flow in habitual smokers and nonsmokers. Dermatology. 1998;197(2):115-8.

Nahidi Y, Javidi Z, Shakeri MT, Farrokhnezhad S, Does cigarette smoking influence acne? Iran J Dermatol. 2012; 15: 80-84.

Rombouts S, Nijsten T, Lambert J. Cigarrete smoking and acne in adolescent: result from a cross-sectional study. J Eur Acad Dermatol Venereol. 2007;21:326-33.

Goldminz D, Bennett R. Cigarette smoking and flap and full thickness graft necrosis. Arch Dermatol. 1991;127:1012-15.

Chuh AA, Zawar V, Wong WC, Lee A. The association of smoking and acne in men in Hong Kong and in India: a retrospective case-control study in primary care settings. Clin Exp Dermatol. 2004;29:597–99.

Mills CM, Petters TJ, Finlay AY. Dose smoking influence acne? Clin Exp Dermatol. 1993;18:100-1.

Sopori M. Effects of cigarette smoke on the immune system. Nat Rev Immunol. 2002;2(5):372-7.

Sopori ML, Kozak W, Savage SM, Geng Y, Soszynski D, Kluger MJ,et al. Effect of nicotine on the immune system: possible regulation of immune responses by central and peripheral mechanisms. Psychoneuroendocrinology. 1998 ;23(2):189-204.

Jemec GB, Linneberg A, Nielsen NH, Frølund L, Madsen F, Jørgensen T. Have oral contraceptives reduced the prevalence of acne? a population-based study of acne vulgaris, tobacco smoking and oral contraceptives. Dermatology. 2002;204(3):179-84.

Firooz A, Sarhangnejad R, Davoudi SM, Nassiri-Kashani M. Acne and smoking: is there a relationship? BMC Dermatol. 2005;24;5:2.

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Published

2017-05-22

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Original Research Articles