DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20214918

Psorolin B: a formulation with synchronized, synergistic scooping of botanicals and associated exodus therapeutic benefit to psoriasis

Amrutha G. V., Aruna V., Gayathri Rajagopal

Abstract


Background: Psoriasis is an auto-inflammatory disease condition, with the clinical symptoms of scaling, inflammation and itching. This condition is triggered by external and internal factors such as environment, seasons and free radicles etc. Psorolin B is a proprietary Siddha Medicine indicated for the reduction in the psoriatic symptoms and also for inhibiting the various triggers of psoriasis

Methods: In the present paper, the formulation is evaluated for its anti-oxidant effect, anti-glycation effect, enzymatic activity reduction i.e., elastase, collagenase, lipoxygenase and reduction in COX1 and COX 2 by following the standard methods.

Results: In the present paper, the formulation is evaluated for its anti-oxidant effect, anti-glycation effect, enzymatic activity reduction i.e., elastase, collagenase, lipoxygenase and reduction in COX1 and COX 2 by following the standard methods. The study results show that the product is able to reduce- free radicle scavenging activity, advanced glycation end products, elastase, collagenase, lipoxygenase and COX1 and COX 2

Conclusions: The study results prove that this product can control the pro-inflammatory mediators by inhibiting the triggering factors like free radicles and advanced glycation end products. This also play a major role in inhibiting the elastase and collagenase that helps in reducing the cell cycle turn over. Complete details of the study are explained the paper.


Keywords


Psoriasis, Pro-inflammatory mediators, Psorolin B, Triggers of psoriasis

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