DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20204572

Phemphigus vulgaris an autoimmune acantholysis: a case report

Abarna Lakshmi Ravi, Rajganesh Ravichandran, Nikhil Cherian Sam, Jaya Shree Dilibatcha, Raveena Pachal Balakrishnan

Abstract


Pemphigus vulgaris is a rare chronic autoimmune skin disease characterized by a flaccid blister filled with clear fluid that arises on the skin or an erythematous base. The keratinocytes separated by the desmoglein present on the desmosomes which clinically manifests as fluid-filled blisters on the skin. We present pemphigus vulgaris with an unknown cause but good recovery after the management with monoclonal antibodies and corticosteroids in a 30-year-old male patient who came to the hospital with complaints of blisters on the epithelial layers of skin on the face and oral mucosa.


Keywords


Pemphigus vulgaris, Autoimmune, Blisters, Desmoglein desmosome

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References


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